Current Trials

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Current Clinical Trials

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AVALON

Open Abdomen Study Comparing ABThera™ Open Abdomen Negative Pressure Therapy System and Barker's Vacuum Packing Technique

Collaboration with UMN Department of Surgery

Funding Source: Solventum US LLC 

Principal Investigator: Todd Costantini, MD

Lead Coordinator: Jessica Gieseke, RN

ClinicalTrials.gov: NCT01016353

FASTEST

FVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial

Collaboration with UMN Department of Neurology

Funding Source: National Institute of Health (NIH) through StrokeNet

Principal Investigator: Christopher Streib, MD

Lead Coordinator: Elizabeth Nierengarten, RN

ClinicalTrials.gov: NCT03496883

HOBIT

Hyperbaric Oxygen Brain Injury Treatment Trial

Collaboration with Hennepin Healthcare - Department of Neurosurgery

Funding Source: National Institute of Health (NIH) through SIREN

Principal Investigator: Thomas Bergman, MD

Lead Coordinators: Elizabeth Nierengarten, RN & Jessica Gieseke, RN

ClinicalTrials.gov: NCT02407028

LIBREXIA-STROKE

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE (LIBREXIA-STROK)

Collaboration with UMN Department of Neurology

Funding Source: Janssen Research & Development, LLC

Principal Investigator: Christopher Streib, MD

Lead Coordinator: Nicole Degerman, RN & Jessica Gieseke, RN

ClinicalTrials.gov: NCT05702034

SISTER

Strategy for Improving Stroke Treatment Response (SISTER)

Collaboration with UMN Department of Neurology

Funding Source: National Institute of Health (NIH) through StrokeNet

Principal Investigator: Muhammad Affan, MD

Lead Coordinator: Jessica Staloch, RN

ClinicalTrials.gov: NCT05948566

STEP

Collaboration with UMN Department of Neurology

Funding Source: National Institute of Health (NIH) through StrokeNet

Principal Investigator: Christopher Streib, MD & Bharathi Jagadeesan, MD

Lead Coordinator: Jessica Staloch, RN

ClinicalTrials.gov: 

T3 ARDS

PHASE II RANDOMIZED, INTERVENTION VERSUS NON-INTERVENTION, MULTI-CENTER STUDY OF THE EFFECTS OF THYROID HORMONE (T3) ON SAFETY/TOLERABILITY AND OXYGENATION IN SUBJECTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)

Collaboration with UMN Department of Pulmonary, Allergy, Critical Care and Sleep Medicine

Funding Source: University of Minnesota Medical Center

Principal Investigator: David Ingbar, MD

Lead Coordinator: Jessica Gieseke, RN

ClinicalTrials.gov: NCT04725110